Embryos and biopsies on the ChIP-ing forecast

Nat Methods. 2006 Aug;3(8):583. doi: 10.1038/nmeth0806-583.

Abstract

UK researchers have devised a method of chromatin immunoprecipitation that requires as little as 100 cells, opening the door to epigenetics studies in primary cells and embryos.

MeSH terms

  • Animals
  • Biopsy / methods
  • Biopsy / trends
  • Chromatin / genetics*
  • Chromatin Immunoprecipitation / instrumentation*
  • Chromatin Immunoprecipitation / methods*
  • Chromosome Mapping / instrumentation*
  • Chromosome Mapping / methods
  • Embryo, Mammalian / physiology*
  • Epigenesis, Genetic / genetics*
  • Histones / genetics*
  • Humans
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Specimen Handling

Substances

  • Chromatin
  • Histones