Risk factors for vitamin D inadequacy among women with osteoporosis: an international epidemiological study

Int J Clin Pract. 2006 Aug;60(8):1013-9. doi: 10.1111/j.1742-1241.2006.01066.x.

Abstract

A serum 25-hydroxyvitamin D [25(OH)D] level of 75 nmol/l (30 ng/ml) has been proposed as the minimum for adequate vitamin D nutrition as lower levels are associated with increases in serum parathyroid hormone in otherwise healthy adults. Amongst 2589 community-dwelling, postmenopausal women with osteoporosis from 18 countries, recruited to determine risk factors for vitamin D inadequacy, 64% had vitamin D inadequacy. General health, education, ethnicity, sun exposure, skin reactivity, diet, recent travel to sunny climates, vitamin D supplementation, body mass index (BMI), season and latitude were assessed using logistic regression models. Asian ethnicity, BMI >or=30 kg/m(2), living in non-equatorial countries, inadequate vitamin D supplementation, poor/fair health, no education about vitamin D, skin reactivity and no recent travel to sunny areas were significant predictors. Several modifiable risk factors are associated with vitamin D inadequacy worldwide, suggesting potentially simple ways to increase vitamin D and improve bone health in postmenopausal women.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Calcifediol / blood
  • Calcifediol / deficiency*
  • Cross-Sectional Studies
  • Environmental Exposure / statistics & numerical data
  • Female
  • Global Health
  • Humans
  • Middle Aged
  • Osteoporosis, Postmenopausal / blood
  • Osteoporosis, Postmenopausal / epidemiology*
  • Residence Characteristics
  • Risk Factors
  • Skin Pigmentation
  • Sunlight
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / epidemiology*

Substances

  • Calcifediol