Coronaviruses in bent-winged bats (Miniopterus spp.)

J Gen Virol. 2006 Sep;87(Pt 9):2461-2466. doi: 10.1099/vir.0.82203-0.


A novel group 1 coronavirus was previously identified in bent-winged bats (Miniopterus spp.). Here, results are described from our ongoing surveillance of these bats for coronaviruses. These findings show that group 1 coronaviruses are endemic in these bat populations in Hong Kong. Genetic analysis of these viruses indicates that there are at least four different, but closely related, group 1 coronaviruses (bat-CoV 1A, 1B, HKU7 and HKU8) circulating in bent-winged bats. Phylogenetic analysis revealed that these group 1 bat coronaviruses have descended from a common ancestor and that these viruses have been established in these bats for a long period of time. These data provide a better understanding of the emergence and evolution of coronaviruses. Bat-CoV 1A and 1B were detected in apparently healthy Miniopterus magnater and Miniopterus pusillus, respectively, on repeated sampling occasions at a single habitat, suggesting that these viruses have established a persistent infection in these populations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Chiroptera / virology*
  • Coronavirus / classification
  • Coronavirus / genetics
  • Coronavirus / isolation & purification*
  • DNA, Viral / genetics
  • Evolution, Molecular
  • Hong Kong
  • Molecular Sequence Data
  • Nucleocapsid Proteins / genetics
  • Phylogeny
  • Sequence Homology, Amino Acid
  • Species Specificity


  • DNA, Viral
  • Nucleocapsid Proteins

Associated data

  • GENBANK/DQ666337
  • GENBANK/DQ666338
  • GENBANK/DQ666339
  • GENBANK/DQ666340
  • GENBANK/DQ666341
  • GENBANK/DQ666342
  • GENBANK/DQ666343
  • GENBANK/DQ666344