Monolithic enantiomer-selective stationary phases for capillary electrochromatography

J Sep Sci. 2006 Jul;29(10):1332-43. doi: 10.1002/jssc.200600030.

Abstract

Monolithic materials have become a well-established format for stationary phases in the field of capillary electrochromatography. Four types of monoliths, namely particle-fixed, silica-based, polymer-based, and molecularly imprinted monoliths, have been utilized as enantiomer-selective stationary phases in CEC. This review summarizes recent developments in the area of monolithic enantiomer-selective stationary phases for CEC. The preparative procedure and the characterization of these columns are highlighted. In addition, the disadvantages and limitations of different monolithic enantiomer-selective stationary phases in CEC are briefly discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acids / chemistry
  • Aptamers, Nucleotide / chemistry
  • Chromatography, High Pressure Liquid* / instrumentation
  • Chromatography, High Pressure Liquid* / methods
  • Molecular Weight
  • Peptides / chemistry
  • Stereoisomerism*

Substances

  • Amino Acids
  • Aptamers, Nucleotide
  • Peptides