Immunohistochemical examination of olfactory mucosa in patients with olfactory disturbance

Ann Otol Rhinol Laryngol. 1990 Mar;99(3 Pt 1):205-10.


The olfactory mucosa was examined by immunohistochemistry in patients with olfactory disturbance: anosmia due to choanal atresia and chronic sinusitis, early-stage common cold, late-stage common cold, and head trauma. The results indicate that the olfactory mucosa of patients with olfactory disturbance shows specific kinds of immunoreactive patterns and that immunohistochemistry is useful for examining the degree of degeneration of pathologic human olfactory mucosa and for clarification of prognosis.

MeSH terms

  • Choanal Atresia / complications
  • Chronic Disease
  • Common Cold / complications
  • Craniocerebral Trauma / complications
  • Humans
  • Immunoenzyme Techniques
  • Keratins / analysis
  • Olfaction Disorders / etiology
  • Olfaction Disorders / metabolism*
  • Olfaction Disorders / pathology
  • Olfactory Mucosa / metabolism*
  • Olfactory Mucosa / pathology
  • Phosphopyruvate Hydratase / analysis
  • S100 Proteins / analysis
  • Sinusitis / complications


  • S100 Proteins
  • Keratins
  • Phosphopyruvate Hydratase