Endocytic recycling pathways: emerging regulators of cell migration

Curr Opin Cell Biol. 2006 Oct;18(5):549-57. doi: 10.1016/j.ceb.2006.08.003. Epub 2006 Aug 9.


The past five years have seen a steady accumulation of data reinforcing the view that Rab-regulated recycling pathways contribute to cell migration. In particular, detailed descriptions have emerged of the mechanisms that recruit integrins and growth factor receptors to Rab4- and Rab11-driven pathways. Recent work provides new insight into the importance of particular recycling events in cell migration within a variety of physiological contexts.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • ADP-Ribosylation Factors / metabolism
  • Animals
  • Cell Membrane / metabolism*
  • Cell Movement / physiology*
  • Endocytosis / physiology*
  • Exocytosis / physiology
  • Integrins / metabolism
  • Receptors, Chemokine / metabolism
  • Receptors, Growth Factor / metabolism
  • Signal Transduction / physiology*
  • rab GTP-Binding Proteins / metabolism


  • Integrins
  • Receptors, Chemokine
  • Receptors, Growth Factor
  • ADP-Ribosylation Factors
  • rab GTP-Binding Proteins