The AtNFXL1 gene encodes a NF-X1 type zinc finger protein required for growth under salt stress

FEBS Lett. 2006 Sep 4;580(20):4851-6. doi: 10.1016/j.febslet.2006.07.079. Epub 2006 Aug 8.

Abstract

The human NF-X1 protein and homologous proteins in eukaryotes represent a class of transcription factors which are characterised by NF-X1 type zinc finger motifs. The Arabidopsis genome encodes two NF-X1 homologs, which we termed AtNFXL1 and AtNFXL2. Growth and survival was impaired in atnfxl1 knock-out mutants and AtNFXL1-antisense plants under salt stress in comparison to wild-type plants. In contrast, 35S: :AtNFXL1 plants showed higher survival rates. The AtNFXL2 protein potentially plays an antagonistic role. The Arabidopsis NF-X1 type zinc finger proteins likely are part of regulatory mechanisms, which protect major processes such as photosynthesis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism*
  • Arabidopsis* / genetics
  • Arabidopsis* / growth & development
  • Arabidopsis* / metabolism
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism*
  • Dehydration*
  • Gene Expression Regulation, Plant
  • Humans
  • Hydrogen Peroxide / metabolism
  • Oxidants / metabolism
  • Plants, Genetically Modified
  • Regulatory Factor X Transcription Factors
  • Salts / metabolism*
  • Transcription Factors / genetics
  • Transcription Factors / metabolism*
  • Zinc Fingers*

Substances

  • Arabidopsis Proteins
  • DNA-Binding Proteins
  • Oxidants
  • Regulatory Factor X Transcription Factors
  • Salts
  • Transcription Factors
  • Hydrogen Peroxide