Acute coronary syndromes and their presentation in Asian and Caucasian patients in Britain

Heart. 2007 Feb;93(2):183-8. doi: 10.1136/hrt.2006.091900. Epub 2006 Aug 16.

Abstract

Objective: To describe and compare demographics and symptom presentation in Asian and Caucasian patients with acute coronary syndromes.

Design: Long-term prospective survey of symptom presentations in two racial groups.

Setting: A London hospital.

Participants: A consecutive series of patients admitted to hospital with acute coronary syndromes between November 2001 and November 2005.

Main outcome measure: Comparison of demographics and location, character, intensity and symptom distribution at presentation between Asian and Caucasian patients.

Results: Asian patients were younger than Caucasian patients (61 v 69 years, p<0.001) and more had diabetes (43% v 17%, p<0.001). Proportionally, more Asian patients had angina (51% v 37%, p<0.001), but more Caucasian patients had myocardial infarction (63% v 49%, p<0.001) and non-ST elevation infarcts (40% v 29%, p<0.001). Men reported smaller areas of discomfort than women. Asian patients more frequently reported discomfort over the rear of their upper bodies compared to Caucasian patients (46% v 25%, p<0.001) and radiation of discomfort to their arms and necks. A higher percentage of Asian than Caucasian patients demonstrated a "classical" location of symptoms (90% v 82%, p<0.001). Patients with diabetes were more likely to feel no discomfort. A higher percentage of Caucasian than Asian patients presented with "silent" events (13% v 6%, p>0.001), with age being a major determinant.

Conclusion: Asian patients were younger, more likely to be diabetic and tended to report a higher intensity of pain and over a greater area of their body, and more frequent discomfort over the rear of their upper thorax than Caucasian patients.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Age Factors
  • Aged
  • Angina Pectoris / diagnosis*
  • Angina Pectoris / ethnology
  • Asian People*
  • Chest Pain
  • Chi-Square Distribution
  • Diabetes Mellitus / ethnology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnosis*
  • Myocardial Infarction / ethnology
  • Pain Threshold
  • Prospective Studies
  • Statistics, Nonparametric
  • Syndrome
  • United Kingdom
  • White People*