Lineage in the vertebrate retina

Trends Neurosci. 2006 Oct;29(10):563-70. doi: 10.1016/j.tins.2006.08.003. Epub 2006 Aug 21.


Recent results are changing the way we think about cell-fate decision mechanisms in the retina. For a long time it was accepted that lineage was not important in retinal cellular determination but, as we review here, new data show that lineage programmes might be at the heart of this process. These programmes are intrinsic, but they are also plastic and are influenced by extrinsic signals.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Cycle / physiology
  • Cell Differentiation / physiology
  • Cell Lineage*
  • Humans
  • Morphogenesis / physiology*
  • Retina / cytology*
  • Retina / embryology*
  • Stem Cells / cytology