Representation of interaural time delay in the human auditory midbrain

Nat Neurosci. 2006 Sep;9(9):1096-8. doi: 10.1038/nn1755. Epub 2006 Aug 20.


Interaural time difference (ITD) is a critical cue to sound-source localization. Traditional models assume that sounds leading at one ear, and perceived on that side, are processed in the opposite midbrain. Using functional magnetic resonance imaging we demonstrate that as the ITDs of sounds increase, midbrain activity can switch sides, even though perceived location remains on the same side. The data require a new model for human ITD processing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustic Stimulation
  • Auditory Pathways / physiology*
  • Auditory Perception / physiology*
  • Cues
  • Ear / physiology
  • Evoked Potentials, Auditory / physiology
  • Humans
  • Magnetic Resonance Imaging / methods
  • Mesencephalon / physiology*
  • Models, Neurological
  • Sound Localization / physiology*
  • Time Factors