Prediction of moderate or severe pulmonary hypertension by main pulmonary artery diameter and main pulmonary artery diameter/ascending aorta diameter in pulmonary embolism

Cardiol Rev. Sep-Oct 2006;14(5):213-4. doi: 10.1097/01.crd.0000181619.87084.8b.

Abstract

We investigated the accuracy of computed tomographic measurements of main pulmonary artery diameter (MPAD) and of MPAD/ascending aorta diameter (AAD) in predicting moderate or severe pulmonary hypertension in 190 patients with acute pulmonary embolism. A pulmonary artery systolic pressure of > or = 50 mm Hg measured by Doppler echocardiography was considered moderate or severe pulmonary hypertension. A MPAD of > 28.6 mm and a MPAD/AAD ratio of > or = 1.00 measured by computed tomography were considered abnormal. A MPAD of > 28.6 mm had a 75% sensitivity and specificity, a 52% positive predictive value, a 89% negative predictive value, a 3.0 likelihood ratio for a positive test, and a 0.33 likelihood ratio for a negative test in predicting moderate or severe pulmonary hypertension. A MPAD/AAD ratio of > or = 1.00 had a 59% sensitivity, a 82% specificity, a 55% positive predictive value, a 84% negative predictive value, a 3.3 likelihood ratio for a positive test, and a 0.50 likelihood ratio for a negative test.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aorta, Thoracic / diagnostic imaging
  • Aorta, Thoracic / pathology*
  • Blood Pressure / physiology
  • Echocardiography, Doppler
  • Female
  • Humans
  • Hypertension, Pulmonary / diagnostic imaging*
  • Hypertension, Pulmonary / etiology*
  • Hypertension, Pulmonary / pathology
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Artery / pathology*
  • Pulmonary Embolism / complications*
  • Pulmonary Embolism / diagnostic imaging
  • Pulmonary Embolism / pathology
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Tomography, Spiral Computed