The changing prevalence of hepatitis B virus infection among men who have sex with men who attended a sexually transmitted infections clinic in Edinburgh, Scotland between 1989 and 2003

Int J STD AIDS. 2006 Aug;17(8):539-42. doi: 10.1258/095646206778145613.

Abstract

The aim of the study was to discover if the prevalence of serological markers of hepatitis B virus infection among men who have sex with men (MSM) who attended a sexually transmitted infections clinic in Edinburgh, Scotland had changed in a 15-year period. This was a retrospective study of 3334 MSM attending the clinic as new patients. Forty-four men (1%) had hepatitis B surface antigenaemia. Overall, sera from 398 (12%) men gave positive results for anti-HBc. The seroprevalence of HBV in men aged 25-34 years and older men declined significantly during the study period. There was no significant change in seropositivity for anti-HBc in men aged 16-24 years. The proportion of men who had been vaccinated previously rose significantly during the most recent three-year period. Although there has been a decline in the prevalence of infection in clinic attendees, there is continued transmission of HBV in the local community.

MeSH terms

  • Adolescent
  • Adult
  • Hepatitis B / epidemiology*
  • Hepatitis B / immunology
  • Hepatitis B / prevention & control
  • Hepatitis B Core Antigens / blood
  • Hepatitis B Surface Antigens / blood
  • Hepatitis B Vaccines / therapeutic use
  • Hepatitis B virus / isolation & purification*
  • Homosexuality*
  • Humans
  • Male
  • Prevalence
  • Retrospective Studies
  • Scotland / epidemiology
  • Sexually Transmitted Diseases, Viral / epidemiology
  • Sexually Transmitted Diseases, Viral / immunology
  • Sexually Transmitted Diseases, Viral / prevention & control
  • Sexually Transmitted Diseases, Viral / virology

Substances

  • Hepatitis B Core Antigens
  • Hepatitis B Surface Antigens
  • Hepatitis B Vaccines