Concise total synthesis of the marine natural product ageladine A

Sudhir R Shengule; Peter Karuso

doi:10.1021/ol061584y

Concise total synthesis of the marine natural product ageladine A

Org Lett. 2006 Aug 31;8(18):4083-4. doi: 10.1021/ol061584y.

Authors

Sudhir R Shengule¹, Peter Karuso

Affiliation

¹ Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia.

PMID: 16928079
DOI: 10.1021/ol061584y

Abstract

A total synthesis of ageladine A has been achieved by exploiting a Pictet-Spengler-type condensation between 2-aminohistamine and 4,5-dibromo-2-formylpyrrole as the key step.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Agelas / chemistry
Animals
Molecular Structure
Pyrroles / chemical synthesis*

Substances

Ageladine A
Pyrroles