Diagnostic evaluation and classification of mastocytosis

Immunol Allergy Clin North Am. 2006 Aug;26(3):515-34. doi: 10.1016/j.iac.2006.05.002.


During the past few years, mastocytosis research has reached important milestones, including the formulation of diagnostic criteria, definition of markers, and targeting of mutated KIT. Important aims for the future are to standardize diagnostic assays and techniques, and to achieve harmonization among centers as a basis for the design of multicenter clinical trials in SM, including the rare ASM and MCL subvariants.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Diagnostic Tests, Routine / standards
  • Humans
  • Immunohistochemistry
  • Mast Cells / pathology
  • Mastocytosis / classification*
  • Mastocytosis / diagnosis*
  • Mastocytosis / genetics
  • Mastocytosis / pathology
  • World Health Organization