Human umbilical cord derived stem cells for the injured heart

Med Hypotheses. 2007;68(1):94-7. doi: 10.1016/j.mehy.2006.06.038. Epub 2006 Aug 24.


The limited ability of the heart to regenerate damaged tissue following a myocardial infarct results in progressive dysfunctions and consequently leads to heart failure. Cell therapy with stem cells for cardiac repair is emerging as an alternative strategy and demonstrates promising results. Recent advances suggest human umbilical cord may be a new source for stem cells. Human umbilical cords are easy to obtain and umbilical cord derived stem cells can be easily extracted and cryopreserved, allowing for individuals to store their own samples for possible future autologous use even if there were no immediate indication that stem cell therapy would be required. Therefore, we hypothesize that human umbilical cord derived stem cells may be the new cell source for the injured heart.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Differentiation
  • Cord Blood Stem Cell Transplantation / methods*
  • Heart Diseases / pathology*
  • Heart Diseases / surgery*
  • Humans
  • Muscle Cells / cytology*
  • Muscle Cells / transplantation
  • Stem Cells / cytology*
  • Umbilical Cord / cytology*