Bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates

Pak J Pharm Sci. 2006 Jul;19(3):214-8.


Present investigation focused on antibacterial potential of aqueous decoction of black pepper (Piper nigrum L.), bay leaf (Laurus nobilis L.), aniseed (Pimpinella anisum L.), and coriander (Coriandum sativum L.) against 176 bacterial isolates belonging to 12 different genera of bacterial population isolated from oral cavity of 200 individuals. The disc diffusion technique was employed. Overall aqueous decoction of black pepper was the most bacterial-toxic exhibited 75% antibacterial activity as compared to aqueous decoction of bay leaf (53.4%) and aqueous decoction of aniseed (18.1%), at the concentration of 10 ml/disc. The aqueous decoction of coriander did not show any antibacterial effect against tested bacterial isolates.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents*
  • Bacteria / drug effects*
  • Child
  • Child, Preschool
  • Coriandrum / chemistry*
  • Female
  • Humans
  • Infant
  • Laurus / chemistry*
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Mouth / microbiology*
  • Pimpinella / chemistry*
  • Piper nigrum / chemistry*
  • Plant Extracts / pharmacology


  • Anti-Bacterial Agents
  • Plant Extracts