[Lacrimal film evaluation of patients with facial dystonia during botulinum toxin type A treatment]

Arq Bras Oftalmol. 2006 May-Jun;69(3):319-22. doi: 10.1590/s0004-27492006000300007.
[Article in Portuguese]

Abstract

Purpose: To determine the effect of botulinum toxin injection in the eyelid on lacrimal film in patients with facial dystonia.

Methods: Twenty-four patients with essential blepharospasm and hemifacial spasm were submitted to botulinum toxin injection and lacrimal film tests were performed before the application and after seven and thirty days.

Results: There was improvement in symptoms of dry eye and rose bengal test, however, the breakup time and Schirmer's test did not show significant variation between pretreatment and after 1 month of follow-up.

Conclusion: The dry eye symptoms in patients with facial dystonia may be attenuated by botulinum toxin due to its possible inhibitory effect on the orbicular muscle leading to a decrease in lacrimal pump.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blepharospasm / complications
  • Blepharospasm / drug therapy*
  • Botulinum Toxins, Type A / therapeutic use*
  • Dry Eye Syndromes / etiology*
  • Dystonic Disorders / drug therapy
  • Female
  • Hemifacial Spasm / complications
  • Hemifacial Spasm / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Neuromuscular Agents / therapeutic use*
  • Prospective Studies
  • Tears / drug effects*
  • Time Factors

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A