Atomic resolution structures in nuclear transport

Methods. 2006 Aug;39(4):342-55. doi: 10.1016/j.ymeth.2006.06.015.


There are currently at least 53 structures of components of nuclear transport in the Protein Databank. In addition to providing critical insights into molecular mechanisms of nuclear transport, these atomic resolution structures provide a large body of information that could guide biochemical and cell biological analyses involving nuclear transport proteins. This paper catalogs 53 crystal and NMR structures of nuclear transport proteins, with the emphasis on providing information useful for mutagenesis and overexpression of recombinant proteins.

MeSH terms

  • Active Transport, Cell Nucleus
  • Amino Acids
  • Biological Transport, Active
  • Cell Nucleus / physiology*
  • Crystallography, X-Ray
  • Karyopherins / chemistry
  • Models, Molecular
  • Nuclear Magnetic Resonance, Biomolecular
  • Protein Conformation*


  • Amino Acids
  • Karyopherins