High-resolution computed tomography (HRCT) should not be considered as a routine assessment method in cystic fibrosis lung disease

Paediatr Respir Rev. 2006 Sep;7(3):197-201. doi: 10.1016/j.prrv.2006.04.005. Epub 2006 Aug 4.


High-resolution computed tomography (HRCT) scanning of the chest should not be considered a routine clinical investigation in the management of CF. Although it demonstrates the detection of early lung damage in children with cystic fibrosis (CF), before HRCT can be considered for routine clinical use in CF it needs to be shown that the benefit from the information obtained will out-weigh potential risks. There is insufficient evidence for the benefit of HRCT for its inclusion into routine care. Moreover, in the absence of information resulting in change in management, HRCT has the potential to increase anxiety for both clinicians and families. In order to advocate for incorporating this technology into routine CF care, further support for its role in management decisions is needed.

Publication types

  • Review

MeSH terms

  • Child
  • Child, Preschool
  • Cystic Fibrosis / diagnosis*
  • Cystic Fibrosis / diagnostic imaging
  • Cystic Fibrosis / therapy*
  • Humans
  • Infant
  • Infant, Newborn
  • Lung / abnormalities
  • Lung Diseases / diagnosis*
  • Lung Diseases / diagnostic imaging
  • Radiographic Image Enhancement
  • Radiography, Thoracic / methods*
  • Time Factors
  • Tomography, X-Ray Computed / methods*