Maximum contrast beamformer for electromagnetic mapping of brain activity

IEEE Trans Biomed Eng. 2006 Sep;53(9):1765-74. doi: 10.1109/TBME.2006.878115.

Abstract

Beamforming technique can be applied to map the neuronal activities from magnetoencephalographic/electroencephalographic (MEG/EEG) recordings. One of the major difficulties of the scalar-type MEG/EEG beamformer is the determination of accurate dipole orientation, which is essential to an effective spatial filter. This paper presents a new beamforming technique which exploits a maximum contrast criterion to maximize the ratio of the neuronal activity estimated in a specified active state to the activity estimated in a control state. This criterion leads to a closed-form solution of the dipole orientation. Experiments with simulation, phantom, and finger-lifting data clearly demonstrate the effectiveness, efficiency, and accuracy of the proposed method.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Brain / physiology*
  • Brain Mapping / methods*
  • Computer Simulation
  • Diagnosis, Computer-Assisted / methods*
  • Electroencephalography / methods*
  • Evoked Potentials, Motor / physiology*
  • Humans
  • Magnetoencephalography / methods*
  • Models, Neurological*