A proposed classification of the immunological diseases

PLoS Med. 2006 Aug;3(8):e297. doi: 10.1371/journal.pmed.0030297.


The formal recognition and genetic understanding of the autoinflammatory diseases has defined mechanisms of self-directed inflammation that are independent of adaptive immunity.

MeSH terms

  • Arthritis, Psoriatic / immunology
  • Autoimmunity / genetics
  • Autoimmunity / immunology
  • Humans
  • Immune System Diseases / classification*
  • Immune System Diseases / therapy
  • Inflammation / genetics
  • Inflammation / immunology

Grant support

DM's research was funded by the Medical Research Council, United Kingdom. MFM's work was supported in part by grants from the Wellcome Trust and the Charitable Foundation of the Leeds Teaching Hospitals.