Properties of Novel and Widely Studied Y-STR Loci in Three South African Populations

Forensic Sci Int. 2007 May 24;168(2-3):154-61. doi: 10.1016/j.forsciint.2006.07.009. Epub 2006 Aug 30.

Abstract

The objective of the present study was to examine the properties of a set of single-copy Y-STR loci to assess their suitability for forensic casework in three South African populations. Three criteria were used to select markers for assessment. Firstly, the single-copy markers of the minimal haplotype were selected based on their established use in forensic studies. Secondly, 8 markers were selected on the basis of high gene diversity values reported for several population studies, and thirdly 19 markers were chosen from a survey of Y-chromosome sequence with selections made primarily on the basis of the number of repeated elements present. Samples were typed from 101 English-speaking Caucasians, 88 Xhosa individuals and 77 Asian Indians. Gene diversity values, the number of alleles identified and the average stutter was determined for each locus.

Publication types

  • Comparative Study

MeSH terms

  • African Continental Ancestry Group / genetics*
  • Asian Continental Ancestry Group / genetics*
  • Chromosomes, Human, Y / genetics*
  • European Continental Ancestry Group / genetics*
  • Forensic Genetics / methods
  • Gene Frequency / genetics
  • Genetic Markers / genetics
  • Genetic Variation / genetics
  • Humans
  • Male
  • Microsatellite Repeats / genetics*
  • South Africa

Substances

  • Genetic Markers