Hepatitis C virus: laboratory surveillance in England and Wales, 1992-2004

Epidemiol Infect. 2007 May;135(4):541-8. doi: 10.1017/S0950268806007138. Epub 2006 Sep 6.


Between 1992 and 2004, a total of 49,819 confirmed hepatitis C infections have been reported to the Health Protection Agency (HPA) by laboratories in England and Wales; the annual number of reports increased from 241 in 1991 to 8149 in 2004. Most reports with a known risk factor were in injecting drug users (87%, 12,438/14,221), but 71% (35,598/49,819) of the total had no reported identified risk. The age-sex distribution of the latter cases was similar to that in injecting drug users. Using names to assign ethnicity, individuals with South Asian names had an older age distribution and a different risk factor profile from non-South Asians. Using published age-specific prevalence data from 1996, it was estimated that around 28,1764 cases of hepatitis C infection exist in England and Wales, and that only 17% of these cases have been reported to the HPA. Surveillance reports continue to provide important information regarding trends in hepatitis C infection in specific risk groups.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Child
  • Child, Preschool
  • England / epidemiology
  • Female
  • Hepacivirus / pathogenicity*
  • Hepatitis C / epidemiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Risk Factors
  • Sex Factors
  • Wales / epidemiology