Since 1996 the Contrast Media Safety Committee of the European Society of Urogenital Radiology (ESUR) has released 19 guidelines regarding safety in relation to the use of radiographic, ultrasonographic as well as magnetic resonance contrast media. The committee has covered both renal and non-renal adverse events as well as other aspects of contrast media. The present paper is an overview of the work accomplished over the last 10 years regarding radiographic iodinated contrast media.