Lupus erythematosus: systemic and cutaneous manifestations

Clin Dermatol. Sep-Oct 2006;24(5):348-62. doi: 10.1016/j.clindermatol.2006.07.014.

Abstract

Skin and joint involvements are the most commonly occurring manifestations of systemic lupus erythematosus. There are 3 forms of cutaneous lupus: chronic cutaneous (discoid) lupus, subacute cutaneous lupus, and acute cutaneous lupus. Joint manifestations are usually not associated with warmth of the joints and may be only associated with pain and swelling. Painful or swollen joints respond rapidly to small or moderate doses of corticosteroids, whereas cutaneous manifestations usually respond to antimalarial drugs. Anti-Ro is associated closely with a photosensitive rash and with subacute lupus.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cardiovascular System / pathology
  • Cardiovascular System / physiopathology
  • Gastrointestinal Tract / pathology
  • Gastrointestinal Tract / physiopathology
  • Humans
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / pathology*
  • Lupus Erythematosus, Systemic / physiopathology
  • Lupus Erythematosus, Systemic / therapy
  • Musculoskeletal Diseases / etiology
  • Musculoskeletal Diseases / pathology*
  • Musculoskeletal Diseases / physiopathology
  • Musculoskeletal Diseases / therapy
  • Musculoskeletal System / pathology
  • Musculoskeletal System / physiopathology
  • Nervous System / pathology
  • Nervous System / physiopathology
  • Respiratory System / pathology
  • Respiratory System / physiopathology
  • Skin / pathology
  • Skin / physiopathology
  • Skin Diseases / etiology
  • Skin Diseases / pathology*
  • Skin Diseases / physiopathology
  • Skin Diseases / therapy