Augur--a computational pipeline for whole genome microbial surface protein prediction and classification

Bioinformatics. 2006 Nov 15;22(22):2819-20. doi: 10.1093/bioinformatics/btl466. Epub 2006 Sep 11.


The analysis of protein function is a challenge and a major bottleneck towards well-annotated and analysed microbial genomes. In particular, bacterial surface proteins present an opportunity for pharmacological intervention and vaccine development. We present Augur, an automatic prediction pipeline that integrates major surface prediction algorithms and enables comparative analysis, classification and visualization for gram-positive bacteria on a genomic scale.


Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Animals
  • Bacterial Proteins / chemistry
  • Computational Biology / methods*
  • Databases, Protein
  • Electronic Data Processing
  • Genes, Bacterial
  • Genome, Bacterial*
  • Markov Chains
  • Membrane Proteins / chemistry*
  • Models, Biological
  • Proteins / chemistry
  • Proteomics / methods*
  • Sequence Analysis, Protein


  • Bacterial Proteins
  • Membrane Proteins
  • Proteins