Folate: a magic bullet or a double edged sword for colorectal cancer prevention?

Gut. 2006 Oct;55(10):1387-9. doi: 10.1136/gut.2006.095463.


Low folate status might inhibit colorectal carcinogenesis and high folate status may promote colorectal carcinogenesis, contradicting findings from epidemiological studies showing an inverse relationship between folate status and risk of colorectal cancer

Publication types

  • Comment

MeSH terms

  • Colorectal Neoplasms / prevention & control*
  • Dietary Supplements
  • Folic Acid / administration & dosage*
  • Folic Acid Deficiency / complications
  • Folic Acid Deficiency / diet therapy*
  • Humans
  • Risk Factors


  • Folic Acid