B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express the CD5 T cell marker

J J Letesson; A Mager; M Mammerickx; A Burny; A Depelchin

B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express the CD5 T cell marker

Leukemia. 1990 May;4(5):377-9.

Authors

J J Letesson¹, A Mager, M Mammerickx, A Burny, A Depelchin

Affiliation

¹ Microbiology and Immunology Unit, Universite Notre Dame de la Paix Namur, Belgium.

PMID: 1697010

Abstract

Though peripheral blood B cells from healthy sheep were known to be devoid of the CD5 T cell marker, it appears from our study that most B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express both the CD5 marker and surface IgM. The possible meaning of this T cell marker expression on B cells from BLV-infected sheep is briefly discussed.

MeSH terms

Animals
Antigens, Differentiation / analysis*
Antigens, Differentiation, T-Lymphocyte / analysis*
B-Lymphocytes / immunology*
CD5 Antigens
Fluorescent Antibody Technique
Immunoglobulin M / analysis
Leukemia Virus, Bovine
Leukemia, Experimental / immunology*
Sheep

Substances

Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CD5 Antigens
Immunoglobulin M