Treatment of angiokeratoma of Fordyce with pulsed dye laser

Dermatol Surg. 2006 Sep;32(9):1147-50. doi: 10.1111/j.1524-4725.2006.32252.x.


Background: Angiokeratomas of Fordyce are typically asymptomatic vascular lesions characterized by blue-to-red papules with a scale surface, most often located on the scrotum. Although considered benign, the lesions may bleed, either spontaneously or secondary to rupture, leading to patient anxiety and social embarrassment.

Objective: The objective was to determine the safety and effectiveness of 585-nm pulsed dye laser for the treatment of angiokeratomas of Fordyce.

Methods: Twelve patients with Fitzpatrick skin type II to IV were treated for angiokeratomas of Fordyce with pulsed dye laser (5.5-8.0 J/cm(2)) in two to six sessions. Lesion clearance was evaluated by two specialists on the basis of digital photographs taken before the first treatment and 2 months after the last treatment.

Results: Seven patients had an excellent response (clearance rating 75%-100%) and five patients had a good response (clearance rating 50%-75%). Transient purpura and pain were present in all patients. Bleeding during treatment occurred in five patients. There were no permanent side effects.

Conclusion: Pulsed dye laser is effective and safe for the treatment of angiokeratoma of Fordyce, with minimum side effects, providing an additional nonablative therapeutic option.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Angiokeratoma / pathology
  • Angiokeratoma / radiotherapy*
  • Follow-Up Studies
  • Genital Neoplasms, Male / pathology
  • Genital Neoplasms, Male / radiotherapy*
  • Humans
  • Low-Level Light Therapy / methods*
  • Male
  • Middle Aged
  • Penile Neoplasms / pathology
  • Penile Neoplasms / radiotherapy
  • Scrotum / pathology
  • Skin Neoplasms / pathology
  • Skin Neoplasms / radiotherapy*
  • Treatment Outcome