Abstract
In vertebrates, hundreds of small nucleolar RNAs (snoRNAs) are processed from pre-mRNA introns. In the September 1 issue of Molecular Cell, Hirose et al. (2006) demonstrate that a spliceosomal intron binding protein, IBP160, couples box C/D snoRNA processing with pre-mRNA splicing in the C1 splicing complex.
MeSH terms
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DNA-Binding Proteins / genetics
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DNA-Binding Proteins / physiology*
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HeLa Cells
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Humans
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Introns / physiology
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RNA Interference
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RNA Precursors / metabolism*
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RNA Processing, Post-Transcriptional
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RNA Splicing*
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RNA, Messenger / metabolism*
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RNA, Small Nucleolar / metabolism*
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Ribonucleoproteins, Small Nucleolar / metabolism*
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Transcription, Genetic
Substances
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DNA-Binding Proteins
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RNA Precursors
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RNA, Messenger
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RNA, Small Nucleolar
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Ribonucleoproteins, Small Nucleolar