SnoRNP biogenesis meets Pre-mRNA splicing

Mol Cell. 2006 Sep 15;23(6):775-6. doi: 10.1016/j.molcel.2006.08.023.

Abstract

In vertebrates, hundreds of small nucleolar RNAs (snoRNAs) are processed from pre-mRNA introns. In the September 1 issue of Molecular Cell, Hirose et al. (2006) demonstrate that a spliceosomal intron binding protein, IBP160, couples box C/D snoRNA processing with pre-mRNA splicing in the C1 splicing complex.

Publication types

  • Comment
  • Review

MeSH terms

  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / physiology*
  • HeLa Cells
  • Humans
  • Introns / physiology
  • RNA Interference
  • RNA Precursors / metabolism*
  • RNA Processing, Post-Transcriptional
  • RNA Splicing*
  • RNA, Messenger / metabolism*
  • RNA, Small Nucleolar / metabolism*
  • Ribonucleoproteins, Small Nucleolar / metabolism*
  • Transcription, Genetic

Substances

  • DNA-Binding Proteins
  • RNA Precursors
  • RNA, Messenger
  • RNA, Small Nucleolar
  • Ribonucleoproteins, Small Nucleolar