Time of origin of substance P-positive neurons in chick dorsal root ganglia

Neurosci Lett. 1990 Jul 3;114(2):135-40. doi: 10.1016/0304-3940(90)90061-d.

Abstract

The birthdates of substance P-positive neurons in chick dorsal root ganglia (DRGs) were determined by a combined immunohistochemical-autoradiographic method. Both substance P-positive and -negative neurons in lumbosacral DRGs were born between days E3 and E6 in ovo. Substance P-positive neurons were born relatively late in comparison to other neurons in the DRG, but did not have unique birthdays.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Autoradiography
  • Chick Embryo
  • DNA Replication
  • Ganglia, Spinal / cytology
  • Ganglia, Spinal / embryology*
  • Immunohistochemistry
  • Neurons / cytology
  • Neurons / physiology*
  • Substance P / analysis*
  • Thymidine / metabolism
  • Tritium

Substances

  • Tritium
  • Substance P
  • Thymidine