Pathology of inflammatory native valvular heart disease

Cardiovasc Pathol. 2006 Sep-Oct;15(5):243-251. doi: 10.1016/j.carpath.2006.04.007.


Rheumatic disease is an important cause of inflammatory native heart valve disease. However, with increased understanding of the pathoetiology of valve disease and valve injury, it is evident that inflammation may play a role in many valve disorders. We are only beginning to understand these complex processes. With increasing knowledge that many of these processes are active, there may be opportunity for intervention or even prevention.

MeSH terms

  • Animals
  • Heart Valve Diseases / etiology
  • Heart Valve Diseases / pathology*
  • Humans
  • Inflammation / etiology
  • Inflammation / pathology*
  • Rheumatic Heart Disease / complications