Objectives: Evaluation of the performance of the EMIT 2000 Tacrolimus assay on the Abbott Architect c8000 analyzer.
Design and methods: Imprecision studies were performed and patient samples were assayed by EMIT assay and by LC-MS/MS.
Results: Limit of quantification was established at 2.8 microg/L. A positive bias of 17.5% between results measured on EMIT and on LC-MS/MS was detected.
Conclusions: EMIT 2000 Tacrolimus assay is suitable for automated analyses of Tacrolimus on the Architect c8000.