The economic burden of HIV in the United States in the era of highly active antiretroviral therapy: evidence of continuing racial and ethnic differences

J Acquir Immune Defic Syndr. 2006 Dec 1;43(4):451-7. doi: 10.1097/01.qai.0000243090.32866.4e.

Abstract

Background: Assessing the economic burden of HIV/AIDS can help to quantify the effect of the epidemic on a population and assist policy makers in allocating public health resources.

Objective: To estimate the economic burden of HIV/AIDS in the United States and provide race/ethnicity-specific estimates.

Methods: We conducted an incidence-based cost-of-illness analysis to estimate the lifetime cost of HIV/AIDS resulting from new infections diagnosed in 2002. Data from the HIV/AIDS Reporting System of the Centers for Disease Control and Prevention were used to determine stage of disease at diagnosis and proportion of cases by race/ethnicity. Lifetime direct medical costs and mortality-related productivity losses were estimated using data on cost, life expectancy, and antiretroviral therapy (ART) use from the literature.

Results: The cost of new HIV infections in the United States in 2002 is estimated at $36.4 billion, including $6.7 billion in direct medical costs and $29.7 billion in productivity losses. Direct medical costs per case were highest for whites ($180,900) and lowest for blacks ($160,400). Productivity losses per case were lowest for whites ($661,100) and highest for Hispanics ($838,000). In a sensitivity analysis, universal use of ART and more effective ART regimens decreased the overall cost of illness.

Conclusion: Direct medical costs and productivity losses of HIV/AIDS resulting from infections diagnosed in 2002 are substantial. Productivity losses far surpass direct medical costs and are disproportionately borne by minority races/ethnicities. Our analysis underscores economic benefits of more effective ART regimens and universal access to ART.

MeSH terms

  • Antiretroviral Therapy, Highly Active*
  • Asian
  • Black People
  • Black or African American
  • CD4 Lymphocyte Count
  • Centers for Disease Control and Prevention, U.S. / statistics & numerical data
  • Cost of Illness
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / economics*
  • HIV Infections / epidemiology
  • HIV Infections / ethnology*
  • HIV-1
  • Health Care Costs / statistics & numerical data
  • Hispanic or Latino
  • Humans
  • Indians, North American
  • Male
  • United States / epidemiology
  • United States / ethnology
  • White People