Invasive zygomycosis: update on pathogenesis, clinical manifestations, and management

Infect Dis Clin North Am. 2006 Sep;20(3):581-607, vi. doi: 10.1016/j.idc.2006.06.003.


Zygomycosis is an increasingly common infection in immunocompromised patients. Advances in the understanding of Zygomycetes pathobiology and the introduction of new drugs with improved activity and tolerability for treatment of zygomycosis have improved the prospects of effectively controlling this devastating infection. Further reductions in mortality will require improved diagnostic and novel therapeutic approaches for this group of aggressive opportunistic molds.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Humans
  • Zygomycosis / classification
  • Zygomycosis / diagnosis*
  • Zygomycosis / drug therapy
  • Zygomycosis / genetics
  • Zygomycosis / microbiology*


  • Antifungal Agents