Endemic mycoses: blastomycosis, histoplasmosis, and sporotrichosis

Infect Dis Clin North Am. 2006 Sep;20(3):645-62, vii. doi: 10.1016/j.idc.2006.07.002.


The endemic mycoses are diverse group of fungi that share several characteristics. They are able to cause disease in healthy hosts, they each occupy a specific ecologic niche in the environment, and they exhibit temperature dimorphism, existing as molds in the environment at temperature of 25 degrees C to 30 degrees C, and as yeasts, or spherules in the case of coccidioidomycosis, at body temperatures. This article discusses histoplasmosis and blastomycosis. Sporotrichosis, which differs in that it is usually a localized lymphocutaneous infection, is included because it shares the characteristics of endemic mycoses.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Blastomycosis / diagnosis*
  • Blastomycosis / drug therapy
  • Histoplasmosis / diagnosis*
  • Histoplasmosis / drug therapy
  • Humans
  • Sporotrichosis / diagnosis*
  • Sporotrichosis / drug therapy


  • Antifungal Agents