Prevalence of age-related maculopathy in the adult population in China: the Beijing eye study

Am J Ophthalmol. 2006 Nov;142(5):788-93. doi: 10.1016/j.ajo.2006.06.001. Epub 2006 Sep 20.

Abstract

Objective: To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China.

Design: Population-based prevalence study.

Methods: The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded by the Wisconsin Age-Related Maculopathy Grading System.

Results: Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122 (1.4%) of 8655 (95% confidence interval [CI] 1.16% to 1.66%) eyes or 63 (1.4%) of 4376 (95% CI 1.09% to 1.79%) subjects, late ARM in 12 (0.14%) of 8655 (95% CI 0.06% to 0.22%) eyes or seven (0.2%) of 4376 (95% CI 0.04% to 0.28%) subjects, and exudative ARM as part of late ARM in seven (0.1%) of 8655 (95% CI 0.02% to 0.14%) eyes or six (0.1%) of 4376 (95% CI 0.03% to 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07%, and 0.07% in the 40-to-44-year age group, to 1.66%, 0.26%, and 0.26% in the 55-to-59-year group, and to 2.99%, 0.90%, and 0.60% in the group aged 75 years and older. ARM was causative for visual impairment (best-corrected visual acuity in the better eye, <20/60 and > or =20/400) or blindness (visual acuity <20/400) in one subject (0.023%).

Conclusions: Visual impairment due to ARM was relatively uncommon in the adult Chinese population in rural and urban regions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Asian Continental Ancestry Group / statistics & numerical data
  • Blindness / epidemiology
  • China / epidemiology
  • Female
  • Humans
  • Macular Degeneration / epidemiology*
  • Male
  • Middle Aged
  • Photography
  • Prevalence
  • Rural Population / statistics & numerical data
  • Urban Population / statistics & numerical data
  • Vision, Low / epidemiology
  • Visually Impaired Persons / statistics & numerical data