Cortical inputs to the CA1 field of the monkey hippocampus originate from the perirhinal and parahippocampal cortex but not from area TE

Neurosci Lett. 1990 Jul 17;115(1):43-8. doi: 10.1016/0304-3940(90)90515-b.

Abstract

We determined the cortical regions that project directly to the CA1 field of the monkey hippocampus by injecting the retrograde tracers Fast blue, Diamidino yellow or WGA-HRP into CA1 and examining the distribution of labeled cells. In the temporal lobe, large numbers of retrogradely labeled cells were observed in the perirhinal and parahippocampal cortices. Only an occasional labeled cell, however, was observed in the unimodal visual area TE. Additional projections to CA1 arose in the dorsal bank of the superior temporal sulcus, in the rostral and retrosplenial portions of the cingulate cortex, in the agranular insular cortex, and in the caudal orbitofrontal cortex.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amidines
  • Animals
  • Axonal Transport
  • Brain / anatomy & histology*
  • Cerebral Cortex / anatomy & histology*
  • Haplorhini / anatomy & histology*
  • Hippocampus / anatomy & histology*
  • Horseradish Peroxidase
  • Pyramidal Tracts / anatomy & histology*
  • Staining and Labeling
  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
  • Wheat Germ Agglutinins

Substances

  • Amidines
  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
  • Wheat Germ Agglutinins
  • diamidino compound 253-50
  • diamidino yellow
  • Horseradish Peroxidase