Primary structure of cAMP-gated channel from bovine olfactory epithelium

FEBS Lett. 1990 Sep 17;270(1-2):24-9. doi: 10.1016/0014-5793(90)81226-e.


The complete amino-acid sequence of the bovine olfactory epithelium adenosine 3',5'-cyclic monophosphate (cAMP)-gated channel has been determined by cloning and sequencing its cDNA. It exhibits a high degree of sequence homology with the cGMP-gated channel of rod photoreceptors, suggesting that cyclic nucleotide-gated channels fall into a new family of genetically related proteins.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cattle
  • Cloning, Molecular
  • Cyclic AMP / physiology*
  • Cyclic GMP / physiology
  • Ion Channel Gating
  • Ion Channels / chemistry*
  • Ion Channels / genetics*
  • Molecular Sequence Data
  • Neurons / chemistry*
  • Olfactory Mucosa / chemistry*
  • Poly A / genetics
  • RNA, Messenger / genetics
  • Sequence Homology, Nucleic Acid


  • Ion Channels
  • RNA, Messenger
  • Poly A
  • Cyclic AMP
  • Cyclic GMP