High body mass index in muscular patients and flank position are risk factors for rhabdomyolysis: case report after laparoscopic live-donor nephrectomy

J Endourol. 2006 Sep;20(9):646-50. doi: 10.1089/end.2006.20.646.

Abstract

Background and purpose: Rhabdomyolysis is well known after traumatic crush injuries or ischemia involving muscles. Postoperatively, it most likely is secondary to surgical positioning and patient muscle mass. We report a case after laparoscopic live-donor nephrectomy.

Case report: A muscular 35-year-old man underwent elective left laparoscopic live-donor nephrectomy in a 70 degrees flank position with four ports. He was in the right-side lying position with hip flexion (flank position) for approximately 4 hours. A kidney bridge had been placed between the iliac crest and the rib cage. Postoperatively, the patient had light-pinkish urine and low urine output. There was marked induration of the buttocks and significant pedal and scrotal edema. With judicious use of alkalinization and diuretics, the patient did not require dialysis, and renal function returned to base level by postoperative day 20. The recipient of the kidney had a normal postoperative course.

Conclusion: Rhabdomyolysis is a syndrome of muscle necrosis and release of intracellular components into the circulation. Acute renal failure secondary to myoglobinuria is a common complication. We currently use little flexion of the table during donor nephrectomy and bring the table to a neutral position immediately after kidney retrieval. Postoperatively, one needs a high index of suspicion for rhabdomyolysis to avoid or at least promptly recognize this rare but potentially serious condition after any operation lasting >or=4 hours.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / etiology
  • Acute Kidney Injury / therapy
  • Adult
  • Body Mass Index*
  • Creatinine / blood
  • Humans
  • Laparoscopy / adverse effects*
  • Laparoscopy / methods
  • Living Donors*
  • Male
  • Myoglobinuria / complications
  • Myoglobinuria / therapy
  • Nephrectomy / adverse effects*
  • Nephrectomy / methods
  • Posture*
  • Rhabdomyolysis / complications
  • Rhabdomyolysis / etiology*
  • Rhabdomyolysis / therapy
  • Risk Factors

Substances

  • Creatinine