Neurocognitive differential diagnosis of dementing diseases: Alzheimer's Dementia, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder

Int J Neurosci. 2006 Nov;116(11):1271-93. doi: 10.1080/00207450600920928.

Abstract

Similarities in presentation of Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder, pose differential diagnosis challenges. The current study identifies specific neuropsychological patterns of scores for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. Neuropsychological domains directly assessed in the study included: immediate memory, delayed memory, confrontational naming, verbal fluency, attention, concentration, and executive functioning. The results reveal specific neuropsychological comparative profiles for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. The identification of these profiles will assist in the differential diagnosis of these disorders and aid in patient treatment.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / diagnosis*
  • Alzheimer Disease / physiopathology
  • Alzheimer Disease / psychology
  • Attention / physiology
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / etiology
  • Cognition Disorders / psychology
  • Dementia / diagnosis*
  • Dementia / physiopathology
  • Dementia / psychology
  • Dementia, Vascular / diagnosis*
  • Dementia, Vascular / physiopathology
  • Dementia, Vascular / psychology
  • Depressive Disorder, Major / diagnosis*
  • Depressive Disorder, Major / physiopathology
  • Depressive Disorder, Major / psychology
  • Diagnosis, Differential
  • Female
  • Humans
  • Language Disorders / diagnosis
  • Language Disorders / etiology
  • Language Disorders / physiopathology
  • Male
  • Memory Disorders / diagnosis
  • Memory Disorders / etiology
  • Memory Disorders / psychology
  • Middle Aged
  • Neuropsychological Tests*
  • Predictive Value of Tests
  • Verbal Behavior / physiology