Lymphatic mapping and sentinel node analysis: current concepts and applications

CA Cancer J Clin. 2006 Sep-Oct;56(5):292-309; quiz 316-7. doi: 10.3322/canjclin.56.5.292.

Abstract

Since the introduction of sentinel node biopsy in 1990 as a minimally invasive surgical technique for the diagnosis of melanoma lymphatic metastases, the number of applications has expanded. We review applications and the current status of sentinel node biopsy in melanoma, breast, colon, gastric, esophageal, head and neck, thyroid, and lung cancer. Variations on techniques specific to each organ are explained, and the current role of sentinel node biopsy in diagnosis and treatment is discussed.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / pathology
  • Female
  • Gastrointestinal Neoplasms / pathology
  • Head and Neck Neoplasms / pathology
  • Humans
  • Lung Neoplasms / pathology
  • Lymphatic Metastasis*
  • Male
  • Neoplasms / pathology*
  • Neoplasms / surgery
  • Sentinel Lymph Node Biopsy*
  • Skin Neoplasms / pathology
  • Thyroid Neoplasms / pathology