Abstract
For the detection of deletion polymorphisms, two pyrene moieties are tethered to an oligodeoxyribonucleotide (ODN) on both sides of the intervening base; one- and two-base deletions can be selectively detected by the strength of the excimer emission.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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DNA Mutational Analysis / methods*
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Gene Deletion*
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Oligodeoxyribonucleotides / chemistry*
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Oligodeoxyribonucleotides / genetics*
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Polymorphism, Genetic / genetics*
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Pyrenes / chemistry*
Substances
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Oligodeoxyribonucleotides
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Pyrenes
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pyrene