Abstract
In recent years, the question of whether breast cancer can be prevented has been examined in a number of large clinical trials, employing either selective estrogen receptor modifiers such as tamoxifen and raloxifene or aromatase inhibitors. In this paper, we review the most prominent studies, all of which are either under way or in follow-up.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Aromatase Inhibitors / therapeutic use
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Breast Neoplasms / enzymology
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Breast Neoplasms / prevention & control*
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Clinical Trials as Topic
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Enzyme Inhibitors / therapeutic use*
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Female
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Humans
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Raloxifene Hydrochloride / therapeutic use
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Selective Estrogen Receptor Modulators / therapeutic use*
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Tamoxifen / therapeutic use
Substances
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Aromatase Inhibitors
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Enzyme Inhibitors
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Selective Estrogen Receptor Modulators
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Tamoxifen
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Raloxifene Hydrochloride