[Cellulite--the greatest skin problem in healthy people? An approach]

J Dtsch Dermatol Ges. 2006 Oct;4(10):861-70. doi: 10.1111/j.1610-0387.2006.06041.x.
[Article in German]


Cellulite or so called orange peel skin affects 80-90 % of all females. It is not considered as a pathological condition but as aesthetically disturbing dimpling of the skin seen most commonly on the thighs and buttocks. Despite its high prevalence, there have been only a few scientific investigations into the pathophysiology of cellulite reflected in the medical literature. A lack of knowledge regarding specific aetiopathogenetic factors and pathogenesis at large currently limits treatment options. The preferred hypotheses about the origin of cellulite include: gender specific dimorphic skin architecture, altered connective tissue septae, vascular changes and inflammatory processes. The most widely discussed management options include: attenuation of aggravating factors, physical procedures including laser therapy and application of topical incorporating actives. The latter approach has been evidence-based with respect to caffeine liposomal cream and retinol cream.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adipose Tissue / cytology*
  • Adipose Tissue / drug effects*
  • Adipose Tissue / surgery
  • Cosmetic Techniques*
  • Dermatologic Agents / administration & dosage*
  • Dermatologic Surgical Procedures
  • Female
  • Humans
  • Male
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians'
  • Reference Values
  • Skin / cytology*
  • Skin / drug effects*
  • Surgery, Plastic / methods*


  • Dermatologic Agents