Split renal function measured by triphasic helical CT

Eur J Radiol. 2007 Feb;61(2):303-9. doi: 10.1016/j.ejrad.2006.09.001. Epub 2006 Sep 29.

Abstract

Purpose: To present a method for calculating split renal function solely from routine triphasic helical computed tomography (CT).

Subjects and methods: We retrospectively included 26 adult patients who received renal scintigraphy and triphasic CT within 4 weeks in the years 2003 and 2004. All scans were performed using a standard abdominal protocol. Split renal function was calculated as relative single-kidney glomerular filtration rate (GFR) using a simplified "two-point Patlak plot" technique. As a reference method, split renal function was determined from renal scintigraphy using the standard technique.

Results: Linear correlation between the two methods was r=0.91, split renal function (CT)=0.0266+0.9573 x split renal function (scintigraphy).

Conclusion: Split renal function can be measured accurately by minimally extended triphasic CT.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Contrast Media / pharmacokinetics*
  • Female
  • Glomerular Filtration Rate
  • Humans
  • Kidney / diagnostic imaging
  • Kidney / physiology*
  • Kidney Function Tests / methods*
  • Male
  • Mathematics
  • Middle Aged
  • Radionuclide Imaging
  • Retrospective Studies
  • Tomography, Spiral Computed*

Substances

  • Contrast Media