Competence-dependent bacteriocin production by Streptococcus gordonii DL1 (Challis)

J Bacteriol. 2007 Feb;189(4):1468-72. doi: 10.1128/JB.01174-06. Epub 2006 Sep 29.

Abstract

The production of streptocins STH(1) and STH(2) by Streptococcus gordonii DL1 (Challis) is directly controlled by the competence regulon, which requires intact comR and comAB loci. The streptocin (sth) locus comprises two functional genes, sthA and sthB. Whereas STH(1) activity requires sthA alone, STH(2) activity depends on both genes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / biosynthesis*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Bacteriocins / biosynthesis*
  • Bacteriocins / genetics
  • DNA-Binding Proteins / metabolism
  • Gene Expression Regulation, Bacterial
  • Hemolysin Proteins / biosynthesis*
  • Hemolysin Proteins / genetics
  • Streptococcus / genetics*
  • Streptococcus / metabolism*

Substances

  • Bacterial Proteins
  • Bacteriocins
  • ComA protein, Bacteria
  • DNA-Binding Proteins
  • Hemolysin Proteins