Abstract
Klebsiella pneumoniae clinical isolates resistant to carbapenems were recovered from 11 patients in the hospital of Sfax, Tunisia. The isolates were closely related as shown by pulsed-field gel electrophoresis, and they produced VIM-4 metallo-enzyme, CTX-M-15 extended-spectrum beta-lactamase, and CMY-4 AmpC enzyme. The bla(VIM-4) gene is part of a class 1 integron.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Proteins / metabolism*
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Base Sequence
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Drug Resistance, Multiple, Bacterial
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Electrophoresis, Gel, Pulsed-Field
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Hospitals, University
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Humans
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Klebsiella Infections / epidemiology*
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Klebsiella Infections / microbiology*
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Klebsiella pneumoniae / drug effects
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / isolation & purification
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Tunisia
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beta-Lactamases / metabolism*
Substances
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Bacterial Proteins
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beta-lactamase CTX-M-15
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AmpC beta-lactamases
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beta-Lactamases
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metallo-beta-lactamase VIM-4, Klebsiella pneumoniae