Drugs, their targets and the nature and number of drug targets

Nat Rev Drug Discov. 2006 Oct;5(10):821-34. doi: 10.1038/nrd2132.


What is a drug target? And how many such targets are there? Here, we consider the nature of drug targets, and by classifying known drug substances on the basis of the discussed principles we provide an estimation of the total number of current drug targets.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Design*
  • Humans
  • Pharmaceutical Preparations / classification*
  • Pharmacology*


  • Pharmaceutical Preparations