Racial and gender disparities in hereditary colorectal cancer risk assessment: the role of family history

J Cancer Educ. Spring 2006;21(1 Suppl):S32-6. doi: 10.1207/s15430154jce2101s_7.

Abstract

Background: In this study, we aimed to examine racial/ethnic and gender differences in self-reported family cancer history knowledge in patients at high risk for hereditary colon cancer syndromes.

Methods: We performed retrospective analysis of all referrals to the University of Chicago High Risk Colon Cancer Clinic between 1995 and 2003.

Results: We found hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis in 17% and 9% of Whites, respectively, and 6% and 0% of Blacks, respectively. Unknown paternal history was found in 6.5% of Whites and 18.9% of Blacks (23% men, 11% women).

Conclusions: Blacks and men had significantly decreased rates of paternal history cancer knowledge.

MeSH terms

  • Adenomatous Polyposis Coli / diagnosis
  • Adenomatous Polyposis Coli / ethnology*
  • African Americans* / genetics
  • African Americans* / statistics & numerical data
  • Asian Americans
  • Chicago / epidemiology
  • Colorectal Neoplasms, Hereditary Nonpolyposis / diagnosis
  • Colorectal Neoplasms, Hereditary Nonpolyposis / ethnology*
  • European Continental Ancestry Group* / genetics
  • European Continental Ancestry Group* / statistics & numerical data
  • Family Health / ethnology
  • Female
  • Genetic Predisposition to Disease / ethnology
  • Genetic Testing / statistics & numerical data*
  • Hispanic Americans
  • Humans
  • Male
  • Retrospective Studies
  • Risk Assessment
  • Sex Distribution